母:35
父:38
之前4胎都健康,俺是第5胎。
现在娘健在,爹已故,所以俺通常跟娘说:俺来自俺爹的XY型未分裂JZ,希望她不要费精力想太多,呵呵。
之前贴吧里Klinefelter兄弟未获得中译版指南前,俺自己未翻译完成的“指南”成因章节如下:
CAUSES
成因
No one knows what puts a couple at risk for conceiving an XXY child.
Advanced maternal age increases the risk for the XXY chromosome count,
but only slightly.
Furthermore, recent studies conducted by NICHD grantee Terry Hassold,
a geneticist at Case Western Reserve University in Cleveland, OH,
show that half the time, the extra chromosome comes from the father.
没人知道导致一对夫妇怀孕XXY孩子的风险。高龄的母亲增加了XXY染色体数的风险,但很轻微。此外,近期的研究,NICHD认可的俄亥俄州克里夫兰凯斯西储大学遗传学者Terry Hassold指示,一半的几率,额外的染色体来自于父亲。
Dr. Hassold explained that cells destined to become sperm or eggs undergo a process known as meiosis.
In this process, the 46 chromosomes in the cell separate,
ultimately producing two new cells having 23 chromosomes each.
Before meiosis is completed, however, chromosomes pair with their corresponding chromosomes and exchange bits of genetic material.
In women, X chromosomes pair;
in men, the X and Y chromosome pair.
After the exchange, the chromosomes separate, and meiosis continues.
Hassold博士陈述了细胞经历减数分裂变成精子或卵子的过程。在此过程中,46条染色体在细胞内分离,最后生成2个各含23条染色体的新细胞。减数分裂完成前,相应的成对的染色体互相交换遗传物质片断。X染色体和X染色体交换配对成为女胎;X染色体和Y染色体交换配对成为男胎。完成父源和母源的遗传物质交换后,生成的受精卵细胞(合子)继续不断染色体分离,完成细胞不断复制再生的减数分裂过程。
In some cases, the Xs or the X chromosome and Y chromosome fail to pair and fail to exchange genetic material.
Occasionally, this results in their moving independently to the same cell, producing either an egg with two Xs, or a sperm having both an X and a Y chromosome.
When a sperm having both an X and a Y chromosome fertilizes an egg having a single X chromosome, or a normal Y-bearing sperm fertilizes an egg having two X
chromosomes, an XXY male is conceived.
有时,X染色体之间、X染色体和Y染色体之间,配对失败或交换遗传物质失败。偶而,这些失败导致他们分别移向同一个细胞,产生出一个双X染色体的卵子,或者同时含有X染色体和Y染色体的精子。当同时含有X染色体和Y染色体的精子使含单条X染色体的卵子受精,或者只含有Y染色体的精子使含有双X染色体的卵子受精时,就怀孕产生XXY男性了。
